How effective are self-management interventions in promoting health-related qualify of life in people after primary treatment for breast cancer? A critical evidence synthesis

Cheng, L. and Kotronoulas, G. (2020) How effective are self-management interventions in promoting health-related qualify of life in people after primary treatment for breast cancer? A critical evidence synthesis. European Journal of Oncology Nursing, 47, 101776. (doi: 10.1016/j.ejon.2020.101776)

Abstract

Purpose: Self-management interventions (SMIs) are designed to empower people living beyond breast cancer and help them adjust to a new normal. This structured review aimed to critically appraise and synthesise up-to-date evidence on the effectiveness of SMIs to promote health-related quality of life (HRQoL) in people with breast cancer in the post-treatment period. Methods: According to PRISMA statement guidelines, MEDLINE, EMBASE and CINAHL were searched for peer-reviewed publications of randomised controlled trials of SMIs. Pre-specified selection criteria were applied to all retrieved records. Methodological quality and risk of bias were evaluated by using the Caldwell framework and Cochrane Collaboration Risk of Bias tool, respectively. Findings were integrated into a narrative critical evidence synthesis. Results: Nine eligible trials were identified that tested nine SMIs. Five SMIs were based on cognitive behaviour therapy (CBT). Eight SMIs targeted recipients' decision-making and taking-action skills. Across trials, gains in one to four domains of HRQoL were reported. SMIs predominantly promoted recipients’ physical and functional well-being, regardless of methodological quality or self-management skills applied, but effect sizes were consistently small. SMIs were mainly prescribed for 12 weeks, but optimal dosage cannot be confirmed currently. SMIs informed by CBT and/or offered through recipient education were marginally more effective. Evidence derived from moderate-to-good quality trials. Conclusions: SMIs are potentially effective after primary treatment for breast cancer, although effect sizes are small and inconsistent across HRQoL domains. More rigorous development and testing is required, while co-production from the early development stages or at the refinement phase is recommended.

• Item Type: Articles
• Keywords: Breast cancer, effectiveness, health-related quality of life, intervention, self-management, survivors.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Kotronoulas, Dr Greg
• Authors: Cheng, L., and Kotronoulas, G.
• College/School: College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Nursing and Health Care
• Journal Name: European Journal of Oncology Nursing
• Publisher: Elsevier
• ISSN: 1462-3889
• ISSN (Online): 1532-2122
• Published Online: 01 June 2020
• Copyright Holders: Copyright © 2020 Elsevier Ltd
• First Published: First published in European Journal of Oncology Nursing 47: 101776
• Publisher Policy: Reproduced in accordance with the publisher copyright policy