Theoretical and Numerical Analysis of mechanical behaviors of a metamaterial-based shape memory polymer stent

Liu, R., Xu, S., Luo, X. and Liu, Z. (2020) Theoretical and Numerical Analysis of mechanical behaviors of a metamaterial-based shape memory polymer stent. Polymers, 12(8), 1784. (doi: 10.3390/polym12081784)

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Abstract

Shape memory polymers (SMPs) have gained much attention in biomedical fields due to their good biocompatibility and biodegradability. Researches have validated the feasibility of shape memory polymer stent in treatment of vascular blockage. Nevertheless, the actual application of SMP stents is still in infancy. To improve the mechanical performance of SMP stent, a new geometric model based on metamaterial is proposed in this study. To verify the feasibility and mechanical behavior of this type of stent, buckling analysis, and in vivo expansion performance of SMP stent are simulated. Numerical results exhibit that stent of a smaller radius behaves a higher critical buckling load and smaller buckling displacement. Besides, a smaller contact area with vessel and smaller implanted stress are observed compared with traditional stents. This suggests that this SMP stent attributes to a reduced vascular restenosis. To characterize the radial strength of SMP stent, an analytical solution is derived by the assumption that the deformation of stent is mainly composed of bending and stretch. The radial strength of SMP stent is assessed in form of radial force. Analytical results reveal that radial strength is depended on the radius of stent and periodic numbers of unit cell in circumferential direction.

Item Type:Articles
Additional Information:This research was funded by the National Natural Science Foundation of China through grant numbers 11811530287 and 11820101001. This research also was founded by the funding of International Exchanges from the Royal Society of London (IEC\NSFC\170202) and the funding of UK Engineering and Physics Research Council (EPSRC) (EP/S030875/1).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Luo, Professor Xiaoyu
Creator Roles:
Luo, X.Writing – review and editing
Authors: Liu, R., Xu, S., Luo, X., and Liu, Z.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:Polymers
Publisher:MDPI
ISSN:2073-4360
ISSN (Online):2073-4360
Copyright Holders:Copyright © 2020 by the authors
First Published:First published in Polymers 12(8):1784
Publisher Policy:Reproduced under a Creative Commons license

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
303232EPSRC Centre for Multiscale soft tissue mechanics with MIT and POLIMI (SofTMech-MP)Xiaoyu LuoEngineering and Physical Sciences Research Council (EPSRC)EP/S030875/1M&S - Mathematics
302241Towards the next generation stenting - The evaluation and study on mechanics behaviour of novel shape memory polymer stentXiaoyu LuoThe Royal Society (ROYSOC)IEC\NSFC\170202M&S - Mathematics