Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study

Moreton, F.C., McCormick, M. and Muir, K.W. (2007) Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study. Stroke, 38(2), pp. 407-410. (doi: 10.1161/01.STR.0000254487.73282.4d)

Abstract

<p><b>Background and Purpose:</b> Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.</p> <p><b>Methods:</b> We retrospectively analyzed insular perfusion on perfusion CT (median 180 minutes after onset) in 35 patients.</p> <p><b>Results:</b> We found no association of hypoperfusion (relative cerebral blood flow <0.51) with early (<6 hours) or delayed (<72 hours) hyperglycemia, or hemispheric lateralization.</p> <p><b>Conclusions:</b> Insular cortex hypoperfusion <6 hours after stroke onset was not associated with hyperglycemia.</p>

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Muir, Professor Keith and Moreton, Dr Fiona
• Authors: Moreton, F.C., McCormick, M., and Muir, K.W.
• College/School: College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience
• Journal Name: Stroke
• Publisher: American Heart Association
• ISSN: 0039-2499
• ISSN (Online): 1524-4628
• Copyright Holders: Copyright © 2007 American Heart Association
• First Published: First published in Stroke 38(2):407-410
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher