Bessell, P. R., Auty, H. K. , Searle, K. R., Handel, I. G., Purse, B. V. and Bronsvoort, B. M. d. C. (2015) Impact of temperature, feeding preference and vaccination on Schmallenberg virus transmission in Scotland. Scientific Reports, 4, 5746. (doi: 10.1038/srep05746) (PMID:25034464) (PMCID:PMC4102919)
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Abstract
First identified in 2011, Schmallenberg virus (SBV) is principally transmitted by Culicoides midges and affects ruminants. Clinical presentation is typified by foetal abnormalities, but despite very high infection rates, relatively few animals present with clinical signs. In this paper we further develop a previously published stochastic mathematical model of SBV spread to investigate the optimal deployment of a vaccine for SBV in Scotland, a country that has experienced only sporadic and isolated cases of SBV. We consider the use of the vaccine under different temperatures and explore the effects of a vector preference for feeding on cattle. We demonstrate that vaccine impact is optimised by targeting it at the high risk areas in the south of Scotland, or vaccinating only cattle. At higher than average temperatures and hence increased transmission potential, the relative impact of vaccination is considerably enhanced. Vaccine impact is also enhanced if vectors feed preferentially on cattle. These findings are of considerable importance when planning control strategies for SBV and also have important implications for management of other arboviruses such as Bluetongue virus. Environmental determinants and feeding preferences should be researched further to inform development of effective control strategies.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Auty, Harriet |
Authors: | Bessell, P. R., Auty, H. K., Searle, K. R., Handel, I. G., Purse, B. V., and Bronsvoort, B. M. d. C. |
College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | Scientific Reports |
Publisher: | Nature Publishing Group |
ISSN: | 2045-2322 |
ISSN (Online): | 2045-2322 |
Published Online: | 18 July 2014 |
Copyright Holders: | Copyright © 2015 The Authors |
First Published: | First published in Scientific Reports 4: 5746 |
Publisher Policy: | Reproduced under a Creative Commons License |
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