The peroxisome: a new player in intestinal epithelial repair.

Bellec, K. and Cordero, J. B. (2020) The peroxisome: a new player in intestinal epithelial repair. Developmental Cell, 53(2), pp. 131-132. (doi: 10.1016/j.devcel.2020.03.023) (PMID:32315607)

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Stem cells drive tissue regeneration due to their capacity to proliferate and differentiate in response to damage. In this issue of Developmental cell, Du et al. reveal a mechanism regulating intestinal stem cell differentiation and epithelial repair following injury, which depends on peroxisomes and their action inducing JAK/Stat signaling and Sox21a.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Cordero, Professor Julia and Bellec, Miss Karen
Authors: Bellec, K., and Cordero, J. B.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Developmental Cell
ISSN (Online):1878-1551
Copyright Holders:Copyright © 2020 Elsevier
First Published:First published in Developmental Cell 53(2):131-132
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
190860Regulation of stem cell function during tissue homeostasis and transformationJulia CorderoWellcome Trust (WELLCOTR)104103/Z/14/ZInstitute of Cancer Sciences