A case of pregnancy with Rhesus antibody and bicornuate uterus - a favourable outcome: a case report

Acharya, S. and Ahmed, S. (2010) A case of pregnancy with Rhesus antibody and bicornuate uterus - a favourable outcome: a case report. Cases Journal, 3, 50. (doi: 10.1186/1757-1626-3-50) (PMID:20205895) (PMCID:PMC2827384)

Abstract

Introduction: In 1% of Rhesus negative women sensitisation occurs without any overt sensitising event during pregnancy. This accounts for late immunisation during a first pregnancy and is responsible for 18-27% of cases of alloimmunisation. The incidence of congenital uterine anomalies in a fertile population is 3.2% of which 5% are bicornuate uterus. Bicornuate uterus can lead to early miscarriages, preterm labor, fetal growth retardation and congenital malformations. Case presentation: A 23-year-old lady in her first pregnancy developed Anti-D antibodies at 28 weeks of gestation without any known sensitising event. In view of increasing anti-D titres, at 36 weeks she was delivered. Incidentally during caesarean section she was found to have bicornuate uterus. The neonate was treated with phototherapy and blood transfusion following delivery. Conclusion: Rhesus antibodies when managed by close monitoring and timely delivery can lead to favourable outcome. Bicornuate uterus does not always lead to complications like miscarriage, growth retardation or preterm labour and does not need any special intervention.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Acharya, Santanu
• Authors: Acharya, S., and Ahmed, S.
• College/School: College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Cases Journal
• Publisher: BioMed Central
• ISSN: 1757-1626
• ISSN (Online): 1757-1626
• Copyright Holders: Copyright © 2010 Acharya and Ahmed
• First Published: First published in Cases Journal 3: 50
• Publisher Policy: Reproduced under a Creative Commons License