Somatic base editing to model oncogenic drivers in breast cancer

Campbell, K. J. and Blyth, K. (2020) Somatic base editing to model oncogenic drivers in breast cancer. Lab Animal, 49, pp. 115-116. (doi: 10.1038/s41684-020-0510-8) (PMID:32152514)

212689.pdf - Accepted Version



Human cancer is a disease of cooperating genetic events that is complex to model in vivo. A new study combines somatic base editing with a mouse model of breast cancer, demonstrating the potential to rapidly investigate the function of disease-specific point mutations.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Blyth, Professor Karen and Campbell, Dr Kirsteen
Authors: Campbell, K. J., and Blyth, K.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Lab Animal
Publisher:Nature Research
ISSN (Online):1548-4475
Published Online:09 March 2020
Copyright Holders:Copyright © 2020 Springer Nature
First Published:First published in Lab Animal 49:115-116
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

University Staff: Request a correction | Enlighten Editors: Update this record