Macpherson, L.M.D. , MacFarlane, T.W., Geddes, D.A.M. and Stephen, K.W. (1992) Assessment of the cariogenic potential of Streptococcus mutans strains and its relationship to in vivo caries experience. Oral Microbiology and Immunology, 7(3), pp. 142-147. (doi: 10.1111/j.1399-302x.1992.tb00527.x) (PMID:1408349)
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Abstract
Strains of Streptococcus mutans isolated from the plaque of 6 subjects were studied using an in vitro model to determine whether differences in their cariogenic potential could be detected, and if so, whether the results correlated with the caries experience of the individuals. Each strain was incubated with a bovine enamel slab and 5% (w/v) sucrose for 24‐h periods. The acidogenic potential was assessed by pH measurement and analysis of acid anion production. Microradio‐graphic and microdensitometric assessment of the enamel, together with measurement of the change in calcium concentration of the reaction mixture were used to determine the demineralizing potential of each strain. Significant differences in cariogenic potential were found between some of the strains tested, and correlations were found between 3 of the test parameters and the decayed‐missing‐filled‐surface score of the individuals. The results suggest that the caries experience of individuals may be related, to some extent, to the cariogenic potential of their S. mutans strains.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Macpherson, Professor Lorna |
Authors: | Macpherson, L.M.D., MacFarlane, T.W., Geddes, D.A.M., and Stephen, K.W. |
College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School |
Journal Name: | Oral Microbiology and Immunology |
Publisher: | Wiley |
ISSN: | 0902-0055 |
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