Wong, M. C.S., Liu, K. Q.L., Wang, H. H.X. , Lee, C. L.S., Kwan, M. W.M., Lee, K. W.S., Cheung, Y., Lee, G. K.Y., Morisky, D. E. and Griffiths, S. M. (2013) Effectiveness of a pharmacist-led drug counseling on enhancing antihypertensive adherence and blood pressure control: a randomized controlled trial. Journal of Clinical Pharmacology, 53(7), pp. 753-761. (doi: 10.1002/jcph.101) (PMID:23677794)
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Abstract
Adherence to antihypertensive medications represents a crucial success factor for optimal blood pressure (BP) control in clinical practice. This study evaluated whether an additional pharmacist‐led medication counseling could achieve better optimal BP control and enhance compliance. In a designated family clinic in a region with similar resident characteristics to Hong Kong, patients taking ≥ one antihypertensive agent with suboptimal compliance were randomly allocated to a brief 3‐minute drug advice (control; n = 161) or pharmacist counseling (intervention; n = 113). The two groups were compared by repeated measure ANOVA at 3‐months and 6‐months with BP control and medication compliance as outcome variables, respectively. The proportions of patients having optimal compliance increased from 0% to 41.1% at 3 months and 61.9% at 6 months (P < 0.001). The proportion of patients having optimal BP control improved from 64.1% at baseline to 74.0% at 3 months and 74.5% at 6 months (P = 0.023). There were no significant differences between the two groups in the changes of BP control and compliance levels. This study implied that even a brief 3‐minute drug advice might lead to improved BP levels among patients on antihypertensive medications in general practice, but did not demonstrate additional effects by pharmacist counseling.
| Item Type: | Articles |
|---|---|
| Additional Information: | Funding: The Direct Grant of the Faculty of Medicine, The Chinese University of Hong Kong. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Wang, Professor Haoxiang |
| Authors: | Wong, M. C.S., Liu, K. Q.L., Wang, H. H.X., Lee, C. L.S., Kwan, M. W.M., Lee, K. W.S., Cheung, Y., Lee, G. K.Y., Morisky, D. E., and Griffiths, S. M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health |
| Journal Name: | Journal of Clinical Pharmacology |
| Publisher: | Wiley |
| ISSN: | 0091-2700 |
| ISSN (Online): | 1552-4604 |
| Published Online: | 16 May 2013 |
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