Ng, C.K.M., Chong, E.Y.W., Roy, V.A.L. , Cheung, K.M.C., Yeung, K.W.K. and Yu, K.N. (2012) Fabrication of micropillar substrates using replicas of alpha-particle irradiated and chemically etched PADC films. Applied Radiation and Isotopes, 70(7), pp. 1432-1435. (doi: 10.1016/j.apradiso.2011.11.019)
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Abstract
We proposed a simple method to fabricate micropillar substrates. Polyallyldiglycol carbonate (PADC) films were irradiated by alpha particles and then chemically etched to form a cast with micron-scale spherical pores. A polydimethylsiloxane (PDMS) replica of this PADC film gave a micropillar substrate with micron-scale spherical pillars. HeLa cells cultured on such a micropillar substrate had significantly larger percentage of cells entering S-phase, attached cell numbers and cell spreading areas.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Vellaisamy, Professor Roy |
| Authors: | Ng, C.K.M., Chong, E.Y.W., Roy, V.A.L., Cheung, K.M.C., Yeung, K.W.K., and Yu, K.N. |
| College/School: | College of Science and Engineering > School of Engineering |
| Journal Name: | Applied Radiation and Isotopes |
| Publisher: | Elsevier |
| ISSN: | 0969-8043 |
| ISSN (Online): | 1872-9800 |
| Published Online: | 18 November 2011 |
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