Yan, L., Chen, W., Zhu, X., Huang, L., Wang, Z., Zhu, G., Roy, V.A.L. , Yu, K.N. and Chen, X. (2013) Folic acid conjugated self-assembled layered double hydroxide nanoparticles for high-efficacy-targeted drug delivery. Chemical Communications, 49(93), pp. 10938-10940. (doi: 10.1039/c3cc45714a) (PMID:24129414)
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Abstract
Enhanced selectivity and efficacy is important for advanced drug delivery. Herein, a novel type of folic acid conjugated self-assembled layered double hydroxide nanoparticles is reported. These nanoparticles have a drug loading capacity of 27 wt% and are able to enter cell nuclei and dramatically improve the efficacy of MTX.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Vellaisamy, Professor Roy |
Authors: | Yan, L., Chen, W., Zhu, X., Huang, L., Wang, Z., Zhu, G., Roy, V.A.L., Yu, K.N., and Chen, X. |
College/School: | College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering |
Journal Name: | Chemical Communications |
Publisher: | Royal Society of Chemistry |
ISSN: | 1359-7345 |
ISSN (Online): | 1364-548X |
Published Online: | 02 October 2013 |
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