De Koning, H. P. (2020) The drugs of sleeping sickness: their mechanisms of action and resistance, and a brief history. Tropical Medicine and Infectious Disease, 5(1), 14. (doi: 10.3390/tropicalmed5010014)
|
Text
206482.pdf - Published Version Available under License Creative Commons Attribution. 674kB |
Abstract
With the incidence of sleeping sickness in decline and genuine progress being made towards the WHO goal of eliminating sleeping sickness as a major public health concern, this is a good moment to evaluate the drugs that ‘got the job done’: their development, their limitations and the resistance that the parasites developed against them. This retrospective looks back on the remarkable story of chemotherapy against trypanosomiasis, a story that goes back to the very origins and conception of chemotherapy in the first years of the 20 century and is still not finished today.
Item Type: | Articles |
---|---|
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | De Koning, Professor Harry |
Authors: | De Koning, H. P. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Tropical Medicine and Infectious Disease |
Publisher: | MDPI |
ISSN: | 2414-6366 |
ISSN (Online): | 2414-6366 |
Copyright Holders: | Copyright © 2020 The Author |
First Published: | First published in Tropical Medicine and Infectious Disease 5(1):14 |
Publisher Policy: | Reproduced under a Creative Commons License |
University Staff: Request a correction | Enlighten Editors: Update this record