Hawkins, N. (2014) Synthesizing clinical evidence for economic evaluation. In: Culyer, A. J. (ed.) Encyclopedia of Health Economics. Elsevier, pp. 382-385. ISBN 9780123756794 (doi: 10.1016/B978-0-12-375678-7.01404-8)
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Abstract
A key aspect of economic evaluation is the estimation of clinical parameters, in particular relating to treatment effects. Network meta-analysis is an extension of pairwise meta analysis that provides estimates of the relative effectiveness of two or more treatments. These are derived from a statistical analysis of a connected network of clinical trial comparisons. Estimates are obtained that correspond to a consistency constraint on the treatment effect scale used for the analysis (δAB=δAC−δBC), where δAB is the indirect estimate of the effect of treatment A compared with treatment B and δAC and δBB represent the direct estimates of the effects of A versus C and B versus C, respectively, and best fit the treatment effect estimates from individual trials.
| Item Type: | Book Sections (Encyclopaedia entry) |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Hawkins, Professor Neil |
| Authors: | Hawkins, N. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Health Economics and Health Technology Assessment |
| Journal Name: | Encyclopedia of Health Economics |
| Publisher: | Elsevier |
| ISBN: | 9780123756794 |
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