Six challenges in the eradication of infectious diseases

Klepac, P., Funk, S., Hollingsworth, T. D., Metcalf, C. J. E. and Hampson, K. (2015) Six challenges in the eradication of infectious diseases. Epidemics, 10, pp. 97-101. (doi: 10.1016/j.epidem.2014.12.001) (PMID:25843393)

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Eradication and elimination are increasingly a part of the global health agenda. Once control measures have driven infection to low levels, the ecology of disease may change posing challenges for eradication efforts. These challenges vary from identifying pockets of susceptibles, improving monitoring during and after the endgame, to quantifying the economics of disease eradication versus sustained control, all of which are shaped and influenced by processes of loss of immunity, susceptible build-up, emergence of resistance, population heterogeneities and non-compliance with control measures. Here we discuss how modelling can be used to address these challenges.

Item Type:Articles
Additional Information:P.K. acknowledges funding from AXA Research Fund. S.F. is supported by a UK Medical Research Council Career Development Award in Biostatistics (MR/K021680/1). C.J.E.M. was funded by the Bill and Melinda Gates Foundation, and the RAPIDD programme of the Science & Technology Directorate, Department of Homeland Security and the Fogarty International Centre, National Institutes of Health. K.H. is supported by the Wellcome Trust and RAPIDD.
Glasgow Author(s) Enlighten ID:Hampson, Professor Katie
Authors: Klepac, P., Funk, S., Hollingsworth, T. D., Metcalf, C. J. E., and Hampson, K.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Epidemics
ISSN (Online):1878-0067
Published Online:12 December 2014
Copyright Holders:Copyright © 2014 The Authors
First Published:First published in Epidemics 10:97-101
Publisher Policy:Reproduced under a Creative Commons License

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