Proof of concept of mass dog vaccination for the control and elimination of canine rabies

Cleaveland, S. , Thumbi, S.M., Sambo, M., Lugelo, A., Lushasi, K., Hampson, K. and Lankester, F.J. (2018) Proof of concept of mass dog vaccination for the control and elimination of canine rabies. Revue scientifique et technique (International Office of Epizootics), 37(2), pp. 559-568. (doi: 10.20506/rst.37.2.2824) (PMID:30747125)

Full text not currently available from Enlighten.


For more than 100 years, canine rabies vaccination has been available as a tool for rabies control and elimination. However, domestic dogs still remain a major reservoir for rabies, and although canine rabies has been eliminated through mass dog vaccination in some parts of the world, the disease continues to kill tens of thousands of people every year in Africa and Asia. This review focuses on the situation on those two continents, presenting evidence to show that canine rabies elimination is both epidemiologically and operationally feasible, and could be achieved across a wide range of settings in Africa and Asia. The challenges of achieving the large-scale, comprehensive dog vaccination coverage that is required are discussed, and opportunities for developing new strategies that generate multiple benefits for human and animal health and welfare are highlighted. Finally, the substantial progress that has been made in developing the tools, partnerships and frameworks needed to move towards global canine rabies elimination is outlined.

Item Type:Articles
Additional Information:The authors also thank the Wellcome Trust for funding support for S.M. Thumbi (Grant No. 110330/Z/15/Z) and K. Hampson (Grant Nos 082715/Z/07/Z and 095787/Z/11/Z).
Glasgow Author(s) Enlighten ID:Hampson, Professor Katie and Cleaveland, Professor Sarah and Lushasi, Mr Kennedy
Authors: Cleaveland, S., Thumbi, S.M., Sambo, M., Lugelo, A., Lushasi, K., Hampson, K., and Lankester, F.J.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Revue scientifique et technique (International Office of Epizootics)
Publisher:Office International des Epizooties
ISSN (Online):0253-1933

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
165644Hierarchical epidemiology: the spread and persistence of infectious diseases in complex landscapesKatie HampsonWellcome Trust (WELLCOTR)095787/Z/11/ZInstitute of Biodiversity, Animal Health and Comparative Medicine