Alfieri, R., Vassalli, M. and Viti, F. (2019) Flow-induced mechanotransduction in skeletal cells. Biophysical Reviews, 11(5), pp. 729-743. (doi: 10.1007/s12551-019-00596-1) (PMID:31529361)
|
Text
202552.pdf - Accepted Version 974kB |
Abstract
Human body is subject to many and variegated mechanical stimuli, actuated in different ranges of force, frequency, and duration. The process through which cells “feel” forces and convert them into biochemical cascades is called mechanotransduction. In this review, the effects of fluid shear stress on bone cells will be presented. After an introduction to present the major players in bone system, we describe the mechanoreceptors in bone tissue that can feel and process fluid flow. In the second part of the review, we present an overview of the biological processes and biochemical cascades initiated by fluid shear stress in bone cells.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Vassalli, Professor Massimo |
| Authors: | Alfieri, R., Vassalli, M., and Viti, F. |
| College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Biophysical Reviews |
| Publisher: | Springer |
| ISSN: | 1867-2450 |
| ISSN (Online): | 1867-2469 |
| Published Online: | 16 September 2019 |
| Copyright Holders: | Copyright © International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany, part of Springer Nature 2019 |
| First Published: | First published in Biophysical Reviews 11(5):729-743 |
| Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
University Staff: Request a correction | Enlighten Editors: Update this record
Altmetric
Altmetric