Potential group B Streptococcus interspecies transmission between cattle and people in Colombian dairy farms

Cobo-Angel, C. G., Jaramillo-Jaramillo, A. S., Palacio-Aguilera, M., Jurado-Vargas, L., Calvo-Villegas, E. A., Ospina-Loaiza, D. A., Rodriguez-Lecompte, J. C., Sanchez, J., Zadoks, R. and Ceballos-Marquez, A. (2019) Potential group B Streptococcus interspecies transmission between cattle and people in Colombian dairy farms. Scientific Reports, 9, 14025. (doi: 10.1038/s41598-019-50225-w) (PMID:31575879) (PMCID:PMC6773701)

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Abstract

Group B Streptococcus (GBS), is a leading cause of neonatal death and an emerging pathogen in adults. Additionally, GBS is a bovine pathogen causing intramammary infections. The likelihood of GBS interspecies transmission is largely unknown. We explored the potential transmission of GBS between cattle and people on dairy farms in Colombia and compared the antimicrobial resistance (AMR) profiles of isolates from both host species. Across 33 farms, throat swabs and rectal swabs were collected from 191 people, and rectal swabs and composite milk samples from 2092 cattle, yielding 60 human isolates and 301 bovine isolates. The majority (64%) of isolates belonged to shared sequence types (ST). Sequence type (ST) 1 was the most common strain in both host species, suggesting that interspecies transmission may be possible. Two members of the bovine-specific clonal complex 61/67 were detected in human samples (ST718 and ST1175), providing evidence for the lack of genuine species barriers. Apparent prevalence of penicillin resistance was surprisingly high in human and bovine isolates. Further investigation of this phenomenon is needed and could lead to modification of standard testing and treatment recommendations in human and veterinary medicine.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Zadoks, Professor Ruth
Authors: Cobo-Angel, C. G., Jaramillo-Jaramillo, A. S., Palacio-Aguilera, M., Jurado-Vargas, L., Calvo-Villegas, E. A., Ospina-Loaiza, D. A., Rodriguez-Lecompte, J. C., Sanchez, J., Zadoks, R., and Ceballos-Marquez, A.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Scientific Reports
Publisher:Nature Research
ISSN:2045-2322
ISSN (Online):2045-2322
Copyright Holders:Copyright © 2019 The Authors
First Published:First published in Scientific Reports 9: 14025
Publisher Policy:Reproduced under a Creative Commons License

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