Coley, S. C., Porter, D. A., Calamante, F., Chong, W. K. and Connelly, A. (1999) Quantitative MR diffusion mapping and cyclosporine-induced neurotoxicity. American Journal of Neuroradiology, 20(8), pp. 1507-1510. (PMID:10512238)
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Publisher's URL: http://www.ajnr.org/content/20/8/1507
Abstract
Apparent diffusion coefficient maps of two patients with cyclosporine-induced neurotoxicity showed areas of increased diffusion that corresponded to the characteristic regions of signal change on routine T2-weighted sequences. The majority of lesions subsequently resolved without residual T2 or diffusion signal alteration. These findings suggest that, in our patients, the neurotoxic effects of cyclosporine resulted in a partially reversible extravasation of fluid into the cerebral interstitium and were not associated with acute ischemia.
| Item Type: | Articles |
|---|---|
| Additional Information: | We thank the Wellcome Trust for financial support. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Porter, Professor David |
| Authors: | Coley, S. C., Porter, D. A., Calamante, F., Chong, W. K., and Connelly, A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
| Journal Name: | American Journal of Neuroradiology |
| Publisher: | American Society of Neuroradiology |
| ISSN: | 0195-6108 |
| ISSN (Online): | 1936-959X |
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