Drop metastases to the pediatric spine revealed with diffusion-weighted MR imaging

Hayes, L. L., Jones, R. A., Palasis, S., Aguilera, D. and Porter, D. A. (2012) Drop metastases to the pediatric spine revealed with diffusion-weighted MR imaging. Pediatric Radiology, 42(8), pp. 1009-1013. (doi: 10.1007/s00247-011-2295-9) (PMID:22052343)

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Abstract

Identifying drop metastases to the spine from pediatric brain tumors is crucial to treatment and prognosis. MRI is currently the gold standard for identifying drop metastases, more sensitive than CSF cytology, but imaging is not uncommonly inconclusive. Although diffusion‐weighted imaging (DWI) of the brain is very useful in the evaluation of hypercellular tumors, DWI of the spine has not been clinically useful in children because of susceptibility artifacts and lack of spatial resolution. A new technique, readout-segmented echo planar imaging (EPI), has improved these images, allowing for identification of hypercellular drop metastases. We report a case that illustrates the utility of spine DWI in the detection of metastatic disease in children with primary central nervous system (CNS) tumors. This case suggests that DWI of the spine with readout-segmented EPI should be included in the evaluation for drop metastases.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Porter, Professor David
Authors: Hayes, L. L., Jones, R. A., Palasis, S., Aguilera, D., and Porter, D. A.
College/School:College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience
Journal Name:Pediatric Radiology
Publisher:Springer
ISSN:0301-0449
ISSN (Online):1432-1998
Published Online:04 November 2011

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