Berry, C., Brosnan, M., Fennell, J., Hamilton, C. and Dominiczak, A. (2001) Oxidative stress and vascular damage in hypertension. Current Opinion in Nephrology and Hypertension, 10(2), pp. 247-255.
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Abstract
Oxidative stress, a state of excessive reactive oxidative species activity, is associated with vascular disease states such as hypertension. In this review, we discuss the recent advances in the field of reactive oxidative species-mediated vascular damage in hypertension. These include the identification of redox-sensitive tyrosine kinases, the characterization of enzymatic sources of superoxide production in human blood vessels, and their relationship with vascular damage in atherosclerosis and hypertension. Finally, recent developments in the search for strategies to attenuate vascular oxidative stress are reviewed.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Berry, Professor Colin and Hamilton, Dr Carlene and Dominiczak, Professor Anna |
Authors: | Berry, C., Brosnan, M., Fennell, J., Hamilton, C., and Dominiczak, A. |
College/School: | College of Medical Veterinary and Life Sciences College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
Journal Name: | Current Opinion in Nephrology and Hypertension |
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