Jazaeri Farsani, S. M. et al. (2015) Identification of a novel human rhinovirus C type by antibody capture VIDISCA-454. Viruses, 7(1), pp. 239-251. (doi: 10.3390/v7010239) (PMID:25606972) (PMCID:PMC4306836)
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Abstract
Causative agents for more than 30 percent of respiratory infections remain unidentified, suggesting that unknown respiratory pathogens might be involved. In this study, antibody capture VIDISCA-454 (virus discovery cDNA-AFLP combined with Roche 454 high-throughput sequencing) resulted in the discovery of a novel type of rhinovirus C (RV-C). The virus has an RNA genome of at least 7054 nt and carries the characteristics of rhinovirus C species. The gene encoding viral protein 1, which is used for typing, has only 81% nucleotide sequence identity with the closest known RV-C type, and, therefore, the virus represents the first member of a novel type, named RV-C54.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Cotten, Professor Matthew |
| Authors: | Jazaeri Farsani, S. M., Oude Munnink, B., Canuti, M., Deijs, M., Cotten, M., Jebbink, M., Verhoeven, J., Kellam, P., Loens, K., Goossens, H., Ieven, M., and van der Hoek, L. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
| Journal Name: | Viruses |
| Publisher: | MDPI |
| ISSN: | 1999-4915 |
| ISSN (Online): | 1999-4915 |
| Published Online: | 19 January 2015 |
| Copyright Holders: | Copyright © 2015 The Authors |
| First Published: | First published in Viruses 7(1): 239-251 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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