Krykféie dicistrovirus: a novel dicistrovirus in velvety free-tailed bats from Brazil

Fumagalli, M. J., de Souza, W. M., de Araujo, J., Modha, S. , Queiroz, L. H., Durigon, E. L., Murcia, P. R. and Figueiredo, L. T. M. (2019) Krykféie dicistrovirus: a novel dicistrovirus in velvety free-tailed bats from Brazil. Infection, Genetics and Evolution, 75, 104036. (doi: 10.1016/j.meegid.2019.104036) (PMID:31499226)

[img]
Preview
Text
195385.pdf - Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

275kB

Abstract

The Dicistroviridae family comprises positive single-stranded RNA viruses that are classified into Picornavirales order. These viruses are identified in arthropod hosts, including some having devastating economic consequences. Here, we described and characterized a novel nearly complete dicistrovirus genome identified in liver samples of velvety free-tailed bats (Molossus molossus) collected in June 2010 in Araçatuba city, São Paulo State, Brazil. This novel virus presents a genome of 9262 nucleotides in length and a typical dicistrovirus genome organization. Based on our phylogenetic analysis and ICTV criteria, we propose this virus as a novel species into the Triatovirus genus. Attempts of viral propagation in Vero E6 and C6/36 cell lines were unsuccessful. The novel dicistrovirus was detected only in one out of nine liver bat samples, representing for the first time an internal organ detection from a representative of this virus family.

Item Type:Articles
Additional Information:This study was supported by the Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil (Grant number No. 13/14929-1, and Scholarships No. 12/24150-9; 15/05778-5; 17/13981-0, 14/20851-8; 16/01414-1; 06/00572-0). PRM was supported by the Medical Research Council of the United Kingdom (Grant MC_UU_120/14/9).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Modha, Ms Sejal and Murcia, Professor Pablo
Authors: Fumagalli, M. J., de Souza, W. M., de Araujo, J., Modha, S., Queiroz, L. H., Durigon, E. L., Murcia, P. R., and Figueiredo, L. T. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Infection, Genetics and Evolution
Publisher:Elsevier
ISSN:1567-1348
ISSN (Online):1567-7257
Published Online:06 September 2019
Copyright Holders:Copyright © 2019 Elsevier B.V.
First Published:First published in Infection, Genetics and Evolution 75: 104036
Publisher Policy:Reproduced in accordance with the publisher copyright policy

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
709011Quinquennial Core FundsMassimo PalmariniMedical Research Council (MRC)MC_UU_12014/9MVLS III - CENTRE FOR VIRUS RESEARCH