de Silva, T. I., Cotten, M. and Rowland-Jones, S. L. (2008) HIV-2: the forgotten AIDS virus. Trends in Microbiology, 16(12), pp. 588-595. (doi: 10.1016/j.tim.2008.09.003) (PMID:18964021)
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Abstract
HIV type 2 (HIV-2), a closely related retrovirus discovered a few years after HIV type 1, causes AIDS in only a minority of infected individuals. Determining why HIV-2 causes asymptomatic infection in most patients could further our understanding of HIV immunopathogenesis. Studies to date have suggested that both enhanced immune responses and lower viral replication could play a role. We summarize the important findings to date and highlight areas that warrant further exploration.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Cotten, Professor Matthew |
| Authors: | de Silva, T. I., Cotten, M., and Rowland-Jones, S. L. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
| Journal Name: | Trends in Microbiology |
| Publisher: | Elsevier (Cell Press) |
| ISSN: | 0966-842X |
| ISSN (Online): | 1878-4380 |
| Published Online: | 27 October 2008 |
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