Combination cryosurgery with hyperthermia in the management of skin metastasis from breast cancer: a case report

Hachisuka, J. , Doi, K. and Furue, M. (2012) Combination cryosurgery with hyperthermia in the management of skin metastasis from breast cancer: a case report. International Journal of Surgery Case Reports, 3(2), pp. 68-69. (doi:10.1016/j.ijscr.2011.10.016) (PMID:22288049) (PMCID:PMC3267272)

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Abstract

Introduction: Skin metastases may impair the quality of life due to physical appearance, odour, and bleeding. Presentation of Case: A 70-year-old woman presented with two enlarging nodules (measuring 12 cm and 3 cm in diameter) consistent with metastatic breast cancer in the left subclavicular area. The larger tumour did not respond to initial cryosurgery. Therefore we added hyperthermia using a disposable body warmer. In addition, the cryosurgery technique was modified to freeze deeper tissue. The entire tumour was covered with dry cotton, to which liquid nitrogen was applied. Twenty weeks later, the tumour became nearly flat and the patient noted improved activity in her daily life. Discussion: Combination treatment with sufficient freezing is important for controlling the tumour, while hyperthermia may accelerate the antitumor effects of cryosurgery. Conclusion: This treatment provides an alternative for unresectable breast cancer skin metastases resistant to chemotherapy and radiotherapy.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Hachisuka, Dr Junichi
Authors: Hachisuka, J., Doi, K., and Furue, M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
Journal Name:International Journal of Surgery Case Reports
Publisher:Elsevier
ISSN:2210-2612
Published Online:10 November 2011
Copyright Holders:Copyright © 2011 Surgical Associates Ltd.
First Published:First published in International Journal of Surgery Case Reports 3(2): 68-69
Publisher Policy:Reproduced under a Creative Commons License

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