Zhang, S., Li, W., Elsayed, M., Tian, P., Clark, A. W. , Wheeler, A. R. and Neale, S. L. (2019) Size-scaling effects for microparticles and cells manipulated by optoelectronic tweezers. Optics Letters, 44(17), pp. 4171-4174. (doi: 10.1364/OL.44.004171) (PMID:31465355)
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Abstract
In this work, we investigated the use of optoelectronic tweezers (OET) to manipulate objects that are larger than those commonly positioned with standard optical tweezers. We studied the forces that could be produced on differently sized polystyrene microbeads and MCF-7 breast cancer cells with light-induced dielectrophoresis (DEP). It was found that the DEP force imposed on the bead/cell did not increase linearly with the volume of the bead/cell, primarily because of the non-uniform distribution of the electric field above the OET bottom plate. Although this size-scaling work focuses on microparticles and cells, we propose that the physical mechanism elucidated in this research will be insightful for other micro-objects, biological samples, and micro-actuators undergoing OET manipulation.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Neale, Professor Steven and Zhang, Dr Shuailong and LI, WEIZHEN and Clark, Professor Alasdair |
Authors: | Zhang, S., Li, W., Elsayed, M., Tian, P., Clark, A. W., Wheeler, A. R., and Neale, S. L. |
College/School: | College of Science and Engineering > School of Engineering College of Science and Engineering > School of Engineering > Biomedical Engineering College of Science and Engineering > School of Engineering > Systems Power and Energy |
Journal Name: | Optics Letters |
Publisher: | Optical Society of America |
ISSN: | 0146-9592 |
ISSN (Online): | 1539-4794 |
Published Online: | 22 July 2019 |
Copyright Holders: | Copyright © 2019 The Authors |
First Published: | First published in Optics Letters 44(17):4171-4174 |
Publisher Policy: | Reproduced under a Creative Commons License |
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