Leishmaniosis causing chronic diarrhoea in a dog

Ward, P. M. , McLaughlan, G., Millins, C. , Mullen, D. and McBrearty, A. R. (2019) Leishmaniosis causing chronic diarrhoea in a dog. Veterinary Record Case Reports, 7(1), e000768. (doi: 10.1136/vetreccr-2018-000768)

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A 10-year-old, male, neutered Podenco Canario was presented for investigation of chronic mixed intestinal diarrhoea and weight loss. The dog was imported from Spain seven years earlier and had not subsequently travelled outside of the UK. Clinical investigations also revealed a lingual mass, right hindlimb lameness, splenomegaly, a non-regenerative anaemia and hyperglobulinaemia. Histopathology of endoscopic gastrointestinal biopsies revealed neutrophilic and histiocytic enteritis and colitis with high numbers of intracytoplasmic organisms suggestive of Leishmania. Similar organisms were identified on cytology from the spleen, bone marrow aspirate and lingual mass. Leishmania PCR was positive on a bone marrow aspirate. Clinical signs resolved with miltefosine and allopurinol treatment. This case describes an atypical presentation of leishmaniosis with chronic diarrhoea which presented for veterinary investigation and treatment, seven years after moving from a Leishmania endemic area to the UK.

Item Type:Articles
Glasgow Author(s) Enlighten ID:McBrearty, Dr Alix and Ward, Miss Trish and Millins, Dr Caroline
Authors: Ward, P. M., McLaughlan, G., Millins, C., Mullen, D., and McBrearty, A. R.
Subjects:S Agriculture > SF Animal culture > SF600 Veterinary Medicine
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Veterinary Record Case Reports
Publisher:BMJ Publishing Group
ISSN (Online):2052-6121
Published Online:08 March 2019
Copyright Holders:Copyright © 2019 British Veterinary Association
First Published:First published in Veterinary Record Case Reports 7(1)e000768
Publisher Policy:Reproduced under a Creative Commons License

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