A versatile and scalable strategy to discrete oligomers

Lawrence, J. et al. (2016) A versatile and scalable strategy to discrete oligomers. Journal of the American Chemical Society, 138(19), pp. 6306-6310. (doi: 10.1021/jacs.6b03127) (PMID:27152711) (PMCID:PMC4879877)

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A versatile strategy is reported for the multigram synthesis of discrete oligomers from commercially available monomer families, e.g., acrylates, styrenics, and siloxanes. Central to this strategy is the identification of reproducible procedures for the separation of oligomer mixtures using automated flash chromatography systems with the effectiveness of this approach demonstrated through the multigram preparation of discrete oligomer libraries (Đ = 1.0). Synthetic availability, coupled with accurate structural control, allows these functional building blocks to be harnessed for both fundamental studies as well as targeted technological applications.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Schmidt, Dr Bernhard
Authors: Lawrence, J., Lee, S.-H., Abdilla, A., Nothling, M. D., Ren, J. M., Knight, A. S., Fleischmann, C., Li, Y., Abrams, A. S., Schmidt, B. V.K.J., Hawker, M. C., Connal, L. A., McGrath, A. J., Clark, P. G., Gutekunst, W. R., and Hawker, C. J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Journal of the American Chemical Society
Publisher:American Chemical Society
ISSN (Online):1520-5126
Published Online:06 May 2016

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