Association between adiposity levels and cognitive impairment in the Chilean older adult population

Concha-Cisternas, Y. et al. (2019) Association between adiposity levels and cognitive impairment in the Chilean older adult population. Journal of Nutritional Science, 8, e33. (doi: 10.1017/jns.2019.24) (PMID:31656624) (PMCID:PMC6794473)

Abstract

Although both obesity and ageing are risk factors for cognitive impairment, there is no evidence in Chile on how obesity levels are associated with cognitive function. Therefore, the aim of the present study was to investigate the association between adiposity levels and cognitive impairment in older Chilean adults. This cross-sectional study includes 1384 participants, over 60 years of age, from the Chilean National Health Survey 2009–2010. Cognitive impairment was evaluated using the Mini-Mental State Examination. BMI and waist circumference (WC) were used as measures of adiposity. Compared with people with a normal BMI, the odds of cognitive impairment were higher in participants who were underweight (OR 4·44; 95 % CI 2·43, 6·45; P < 0·0001), overweight (OR 1·86; 95 % CI 1·06, 2·66; P = 0·031) and obese (OR 2·26; 95 % CI 1·31, 3·21; P = 0·003). The associations were robust after adjustment for confounding variables. Similar results were observed for WC. Low and high levels of adiposity are associated with an increased likelihood of cognitive impairment in older adults in Chile.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Waddell, Miss Heather and Ho, Dr Frederick and Sillars, Dr Anne and Celis, Dr Carlos and Gray, Professor Stuart and Petermann-Rocha, Mrs Fanny
• Authors: Concha-Cisternas, Y., Lanuza, F., Waddell, H., Sillars, A., Leiva, A.M., Troncoso, C., Martinez, M.A., Villagrán, M., Mardones, L., Martorell, M., Nazar, G., Ulloa, N., Labraña, A.M., Diaz-Martinez, X., Sadarangani, K., Alvarez, C., Ramirez-Campillo, R., Garrido-Mendez, A., Luarte, C., Ho, F., Gray, S. R., Petermann-Rocha, F., and Celis-Morales, C.
• College/School: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health; College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Journal of Nutritional Science
• Publisher: Cambridge University Press
• ISSN: 2048-6790
• ISSN (Online): 2048-6790
• Published Online: 09 October 2019
• Copyright Holders: Copyright © 2019 The Authors
• First Published: First published in Journal of Nutritional Science 8:e33
• Publisher Policy: Reproduced under a Creative Commons License