Barclay, A., Paul, L., MacFarlane, N. and McFadyen, A. (2019) The effect of cycling using active-passive trainers on spasticity, cardiovascular fitness, function and quality of life in people with moderate to severe Multiple Sclerosis (MS); a feasibility study. Multiple Sclerosis and Related Disorders, 34, pp. 128-134. (doi: 10.1016/j.msard.2019.06.019)
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Abstract
Background: Exercise options for those with moderate to high levels of disability are limited. The aim of the study was to evaluate the feasibility of a progressive, four week lower limb cycling programme using active-passive trainers (APT's) on spasticity, cardiovascular fitness, function and quality of life in people with moderate to severe MS. Methods: Participants were in-patients in the Physical Disability Rehabilitation Unit, Queen Elizabeth University Hospital, Glasgow, UK and randomised to APT + usual care or usual care only. The APT group received 30 min of APT (2 min passive warm up, 26 min active cycling, 2 min passive cool down),five days per week for 4 weeks. Outcome measures; Oxygen Uptake Efficiency Slope, Modified Ashworth Scale, Multiple Sclerosis Spasticity Scale, Functional Independence Measure, Timed 25 foot walk test and the MSQOL-54, were taken before and after the intervention period. Symmetry, distance cycled and active participation were also recorded for each cycling session .Results:24 participants were recruited, 15 to the intervention and 9 to the control group. There was a 100% adherence to the intervention and a significant increase in average speed, power output and distance cycled (p< 0.001 for each) over the four weeks. There were no adverse events and both groups improved in average scores for all outcome measures. Conclusions: APT cycling was well tolerated, while the cycling parameters improved it was difficult to separate the effects of the therapy programme and APT cycling. A longer duration, fully powered trial in a community setting is merited.
Item Type: | Articles |
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Additional Information: | This study was funded by the Chartered Society of Physiotherapy grant no. PRF/15/B01, Physiotherapy fund. |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | MacFarlane, Professor Niall and Barclay, Alison |
Authors: | Barclay, A., Paul, L., MacFarlane, N., and McFadyen, A. |
College/School: | College of Medical Veterinary and Life Sciences > School of Life Sciences College of Medical Veterinary and Life Sciences |
Journal Name: | Multiple Sclerosis and Related Disorders |
Publisher: | Elsevier |
ISSN: | 2211-0348 |
ISSN (Online): | 2211-0356 |
Published Online: | 18 June 2019 |
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