Non-coding RNAs in primary liver cancer

Ghidini, M. and Braconi, C. (2015) Non-coding RNAs in primary liver cancer. Frontiers in Medicine, 2, 36. (doi: 10.3389/fmed.2015.00036) (PMID:26131450) (PMCID:PMC4469108)

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Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with poor prognosis and limited therapeutic options. Over the past few years, many studies have evaluated the role of non-coding RNAs (ncRNAs) in hepatocarcinogenesis and tumor progression. ncRNAs were shown to have diagnostic, prognostic, and therapeutic potential in HCC. In this manuscript, we review the latest major discoveries concerning microRNAs and long ncRNAs in HCC pathogenesis, and discuss the potentials and the limitations for their use in clinical practice.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Braconi, Dr Chiara
Authors: Ghidini, M., and Braconi, C.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Frontiers in Medicine
Publisher:Frontiers Media
ISSN (Online):2296-858X
Copyright Holders:Copyright © 2015 Ghidini and Braconi
First Published:First published in Frontiers in Medicine 2: 36
Publisher Policy:Reproduced under a Creative Commons License

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