Ackermann, T. and Tardito, S. (2019) Cell culture medium formulation and its implications in cancer metabolism. Trends in Cancer, 5(6), pp. 329-332. (doi: 10.1016/j.trecan.2019.05.004) (PMID:31208694) (PMCID:PMC6557711)
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Abstract
Historic cell culture media were designed to ensure continuous cancer cell proliferation in vitro. However, their composition does not recapitulate the nutritional environment of the tumor. Recent studies show that novel media formulations alleviate the nonphysiological constraints imposed by historic media, and lead to cell culture results that are more relevant to tumor metabolism.
| Item Type: | Articles |
|---|---|
| Additional Information: | This work was supported by Cancer Research UK (C596/A17196, Award 23982). |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Tardito, Dr Saverio |
| Authors: | Ackermann, T., and Tardito, S. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Trends in Cancer |
| Publisher: | Elsevier (Cell Press) |
| ISSN: | 2405-8033 |
| ISSN (Online): | 2405-8033 |
| Published Online: | 29 May 2019 |
| Copyright Holders: | Copyright © 2019 Elsevier Inc. |
| First Published: | First published in Trends in Cancer 5(6): 329-332 |
| Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
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