Current management and novel therapeutic strategies for refractory ascites and hepatorenal syndrome

Suzuki, H. and Stanley, A.J. (2001) Current management and novel therapeutic strategies for refractory ascites and hepatorenal syndrome. QJM: An International Journal of Medicine, 94(6), pp. 293-300. (doi: 10.1093/qjmed/94.6.293) (PMID:11391027)

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Abstract

The circulatory disturbances seen in advanced cirrhosis lead to the development of ascites, which can become refractory to diet and medical therapy. These abnormalities may progress and cause a functional renal failure known as the hepatorenal syndrome. Management of refractory ascites and hepatorenal syndrome is a therapeutic challenge, and if appropriate, liver transplantation remains the best treatment. New therapeutic options have recently appeared, including the transjugular intrahepatic portosystemic shunt and selective splanchnic vasoconstrictor agents, which may improve renal function and act as a bridge to transplantation.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Stanley, Dr Adrian
Authors: Suzuki, H., and Stanley, A.J.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:QJM: An International Journal of Medicine
Publisher:Oxford University Press
ISSN:1460-2725
ISSN (Online):1460-2393

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