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Intravital imaging of host-parasite interactions in skin and adipose tissues

De Niz, M., Meehan, G. R. , Brancucci, N. M.B. , Marti, M. , Rotureau, B., Figueiredo, L. M. and Frischknecht, F. (2019) Intravital imaging of host-parasite interactions in skin and adipose tissues. Cellular Microbiology, 21(5), e13023. (doi: 10.1111/cmi.13023) (PMID:30825872)

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Abstract

Intravital microscopy (IVM) allows the visualization of how pathogens interact with host cells and tissues in living animals in real time. This method has enabled key advances in our understanding of host-parasite interactions under physiological conditions. A combination of genetics, microscopy techniques and image analysis have recently facilitated the understanding of biological phenomena in living animals at cellular and sub-cellular resolution. In this review, we summarize findings achieved by intravital microscopy of the skin and adipose tissues upon infection with various parasites and we present a view into possible future applications of this method.

Item Type:	Articles
Keywords:	Intravital imaging, parasite, adipose skin, plasmodium, trypanosomes toxoplasmosis.
Status:	Published
Refereed:	Yes
Glasgow Author(s) Enlighten ID:	Marti, Professor Matthias and Meehan, Dr Gavin and Brancucci, Dr Nicolas and De Niz, Dr Mariana
Authors:	De Niz, M., Meehan, G. R., Brancucci, N. M.B., Marti, M., Rotureau, B., Figueiredo, L. M., and Frischknecht, F.
Subjects:	Q Science > QR Microbiology > QR180 Immunology
College/School:	College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
Journal Name:	Cellular Microbiology
Publisher:	Wiley
ISSN:	1462-5814
ISSN (Online):	1462-5822
Published Online:	02 March 2019
Copyright Holders:	Copyright © 2019 The Authors
First Published:	First published in Cellular Microbiology 21(5):e13023
Publisher Policy:	Reproduced in accordance with the publisher copyright policy

University Staff: Request a correction | Enlighten Editors: Update this record

Funder and Project Information

Project Code	Award No	Project Name	Principal Investigator	Funder's Name	Funder Ref	Lead Dept
52507	2	Cytoadherence-mediated pathology in cerebral malaria	James Brewer	Wellcome Trust (WELLCOTR)	095507/Z/11/A	III -IMMUNOLOGY

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Deposit and Record Details

ID Code:	181437
Depositing User:	Dr Gavin Meehan
Datestamp:	11 Mar 2019 09:15
Last Modified:	06 Sep 2022 15:01
Date of acceptance:	8 February 2019
Date of first online publication:	2 March 2019
Date Deposited:	11 March 2019
Data Availability Statement:	No