Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study

Leitch, J.A., Sutcliffe, N. and Kenny, G.N. (2003) Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study. British Dental Journal, 194(1), pp. 43-45.

Abstract

OBJECTIVE: To assess the safety and efficacy of a new patient-maintained propofol system for conscious sedation in dentistry. DESIGN: Prospective clinical trial SETTING: Department of Sedation, Glasgow Dental Hospital and School, 2001 SUBJECTS AND METHODS: Patients scheduled for oral surgery with conscious sedation. Exclusions included ASA IV -V, inability to use the handset, opioid use and severe respiratory disease. INTERVENTIONS: Patients were given intravenous propofol to a level of 1.0 microg/ml (reducing from 1.5 microg/ml) using a target controlled infusion system, they then controlled their sedation level by double-clicking a handset which on each activation increased the propofol concentration by 0.2 microg/ml. MAIN OUTCOME MEASURES: Oxygen saturation, patient satisfaction, and surgeon satisfaction. RESULTS: Twenty patients were recruited, 16 female and four male. Nineteen patients completed sedation and treatment successfully. Mean lowest oxygen saturation was 94%. No patients were over-sedated. All patients successfully used the system to maintain a level of sedation adequate for their comfort. Patient and surgeon satisfaction were consistently high. CONCLUSIONS: Initial experience with this novel system has confirmed safety, patient satisfaction and surgeon satisfaction.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: UNSPECIFIED
• Authors: Leitch, J.A., Sutcliffe, N., and Kenny, G.N.
• Subjects: R Medicine > RK Dentistry; R Medicine > RD Surgery
• College/School: College of Medical Veterinary and Life Sciences
• Journal Name: British Dental Journal
• Publisher: Nature Publishing Group
• ISSN: 0007-0610
• Copyright Holders: © Copyright British Dental Journal
• First Published: First published in the British Dental Journal 194(1):43 - 45
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher