Imaging cancer metabolism with Positron Emission Tomography (PET)

Witney, T. H. and Lewis, D. Y. (2019) Imaging cancer metabolism with Positron Emission Tomography (PET). In: Haznadar, M. (ed.) Cancer Metabolism: Methods and Protocols. Series: Methods in Molecular Biology, 1928. Springer, pp. 29-44. ISBN 9781493990269 (doi: 10.1007/978-1-4939-9027-6_2)

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Abstract

Positron emission tomography (PET) enables the noninvasive spatiotemporal analysis of cancer metabolism in vivo. Both natural and nonnatural PET tracers have been developed to assess metabolic pathways during tumorigenesis, cancer progression, and metastasis. Here we describe the dynamic in vivo PET/CT imaging of the glucose analogue [ F]fluoro-2-deoxy-D-glucose (FDG), taking into consideration the methodology for alternative metabolic PET substrates.

Item Type:Book Sections
Status:Published
Glasgow Author(s) Enlighten ID:Lewis, Dr David
Authors: Witney, T. H., and Lewis, D. Y.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Methods in molecular biology (Clifton, N.J.)
Publisher:Springer
ISSN:1940-6029
ISBN:9781493990269

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