SERRS immunoassay for quantitative human CRP analysis

Campbell, F. M., Ingram, A., Monaghan, P., Cooper, J. , Sattar, N., Eckersall, P. D. and Graham, D. (2008) SERRS immunoassay for quantitative human CRP analysis. Analyst, 133(10), pp. 1355-1357. (doi: 10.1039/b808087a) (PMID:18810282)

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Publisher's URL: http://dx.doi.org/10.1039/b808087a

Abstract

SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Campbell, Dr Fiona and Eckersall, Professor David and Cooper, Professor Jonathan and Monaghan, Dr Paul and Sattar, Professor Naveed
Authors: Campbell, F. M., Ingram, A., Monaghan, P., Cooper, J., Sattar, N., Eckersall, P. D., and Graham, D.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Infection & Immunity
College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Analyst
ISSN:0003-2654
ISSN (Online):1364-5528

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
379081Optical biosensors in human and animal healthPeter EckersallBiotechnology and Biological Sciences Research Council (BBSRC)BB/C003683/1Infection Immunity and Inflammation Life Sciences