Clinical findings and outcome of dogs with unilateral masticatory muscle atrophy

Milodowski, E. J., Amengual-Batle, P., Beltran, E., Gutierrez-Quintana, R. and De Decker, S. (2019) Clinical findings and outcome of dogs with unilateral masticatory muscle atrophy. Journal of Veterinary Internal Medicine, 33(2), pp. 735-742. (doi: 10.1111/jvim.15373) (PMID:30556930) (PMCID:PMC6430959)

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Abstract

Background: Little is known about the spectrum of underlying disorders in dogs with unilateral masticatory muscle (MM) atrophy. Objectives: To evaluate the clinical presentation, magnetic resonance imaging (MRI) findings, and outcome of dogs with unilateral MM atrophy. Animals: Sixty‐three client‐owned dogs. Methods: The medical database was retrospectively reviewed for dogs that underwent MRI for evaluation of unilateral MM atrophy. Imaging studies were reviewed and follow‐up information was obtained from telephone interviews. Results: Presumptive trigeminal nerve sheath tumor (pTNST) was diagnosed in 30 dogs (47.6%); survival time varied from 1 day to 21 months (median, 5 months). Other extra‐axial mass lesions were observed in 13 dogs (20.6%); survival time varied from 6 days to 25 months (median, 2.5 months). In 18 dogs (28.6%), no abnormalities were observed on MRI; neurological signs only progressed in 1 dog. Diagnosis had a significant influence on the type of neurological abnormalities, with additional neurological deficits observed in most dogs with pTNST and in all dogs with other extra‐axial mass lesions. Diagnosis had a significant effect on euthanasia at the time of diagnosis and likelihood of neurological deterioration. Dogs with mass lesions were more likely to be euthanized or experience neurological deterioration, whereas these outcomes occurred less often in dogs in which no causative lesion could be identified. Conclusions and Clinical Importance: Trigeminal nerve sheath tumors should not be considered the only cause of unilateral MM atrophy. Our results illustrate the importance of performing a neurological examination and MRI when evaluating dogs with unilateral MM atrophy.

Item Type:Articles
Keywords:Cranial nerves, facial asymmetry, neuritis, trigeminal nerve sheath tumor.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gutierrez Quintana, Mr Rodrigo and Amengual Batle, Pablo
Authors: Milodowski, E. J., Amengual-Batle, P., Beltran, E., Gutierrez-Quintana, R., and De Decker, S.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Journal of Veterinary Internal Medicine
Publisher:Wiley
ISSN:0891-6640
ISSN (Online):1939-1676
Published Online:17 December 2018
Copyright Holders:Copyright © 2018 The Authors
First Published:First published in Journal of Veterinary Internal Medicine 33(2):735-742
Publisher Policy:Reproduced under a Creative Commons License

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