Viral diversity of Rhipicephalus microplus parasitizing cattle in southern Brazil

Souza, W. M. d. et al. (2018) Viral diversity of Rhipicephalus microplus parasitizing cattle in southern Brazil. Scientific Reports, 8, 16315. (doi: 10.1038/s41598-018-34630-1) (PMID:30397237) (PMCID:PMC6218518)

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Abstract

Ticks are ectoparasites spread worldwide and are well known as vectors of many viruses of great importance to human and animal health. However, the viral diversity in ticks is still poorly understood, particularly in South America. Here we characterized the viral diversity present in Rhipicephalus microplus parasitizing cattle in the southern region of Brazil using metagenomics. Our study revealed the presence of viruses that had not been previously described in the region, including lihan tick virus (Phenuiviridae family) and wuhan tick virus 2 (Chuviridae family), as well as expands the biogeography of jingmen tick virus (Flaviviridae family) in Brazil. Also, we described three novel tymoviruses (Tymovirales order), named guarapuava tymovirus-like 1 to 3. We described the genomic and phylogenetic characterization of these viruses. Our study sheds light on the viral diversity of Rhipicephalus microplus in South America, and also expands the biogeography of tick viruses that were previously described only in Asia.

Item Type:Articles
Additional Information:Tis study was supported by the Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil (Grant No. 13/14929-1 and 14/02438-6). WMS (Scholarships No. 12/24150-9, 15/05778-5 and 17/13981-0), MRF (FAPESP: Scholarships No. 14/20851-8), MJF (FAPESP: Scholarships No. 16/01414-1). PRM was supported by the Medical Research Council of the United Kingdom (Grant MC_UU_120/14/9).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Modha, Ms Sejal and Murcia, Dr Pablo
Authors: Souza, W. M. d., Fumagalli, M. J., Torres Carrasco, A. d. O., Romeiro, M. F., Modha, S., Seki, M. C., Gheller, J. M., Daffre, S., Nunes, M. R. T., Murcia, P. R., Acrani, G. O., and Figueiredo, L. T. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Scientific Reports
Publisher:Nature Research
ISSN:2045-2322
ISSN (Online):2045-2322
Copyright Holders:Copyright © 2018 The Authors
First Published:First published in Scientific Reports 8:16315
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
709011Quinquennial Core FundsMassimo PalmariniMedical Research Council (MRC)MC_UU_12014/9MVLS III - CENTRE FOR VIRUS RESEARCH