Jackson, M., Marks, L., May, G. H.W. and Wilson, J. B. (2018) The genetic basis of disease. Essays In Biochemistry, 62(5), pp. 643-723. (doi: 10.1042/EBC20170053)
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Abstract
Genetics plays a role, to a greater or lesser extent, in all diseases. Variations in our DNA and differences in how that DNA functions (alone or in combinations), alongside the environment (which encompasses lifestyle), contribute to disease processes. This review explores the genetic basis of human disease, including single gene disorders, chromosomal imbalances, epigenetics, cancer and complex disorders, and considers how our understanding and technological advances can be applied to provision of appropriate diagnosis, management and therapy for patients.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Wilson, Professor Joanna and May, Dr Gerhard and Jackson, Dr Maria and Marks, Dr Leah |
Authors: | Jackson, M., Marks, L., May, G. H.W., and Wilson, J. B. |
College/School: | College of Medical Veterinary and Life Sciences > School of Life Sciences College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing College of Medical Veterinary and Life Sciences > School of Molecular Biosciences |
Journal Name: | Essays In Biochemistry |
Publisher: | Portland Press |
ISSN: | 0071-1365 |
ISSN (Online): | 1744-1358 |
Copyright Holders: | Copyright © 2018 The Authors |
First Published: | First published in Essays In Biochemistry 62(5): 643-723 |
Publisher Policy: | Reproduced under a Creative Commons License |
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