Francone, A., Kehoe, T., Obieta, I., Saez-Martinez, V., Bilbao, L., Khokhar, A., Gadegaard, N. , Simao, C., Kehagias, N. and Sotomayor Torres, C. (2018) Integrated 3D hydrogel waveguide out-coupler by step-and-repeat thermal nanoimprint lithography: a promising sensor device for water and pH. Sensors, 18(10), 3240. (doi: 10.3390/s18103240) (PMID:30261650) (PMCID:PMC6210174)
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Abstract
Hydrogel materials offer many advantages for chemical and biological sensoring due to their response to a small change in their environment with a related change in volume. Several designs have been outlined in the literature in the specific field of hydrogel-based optical sensors, reporting a large number of steps for their fabrication. In this work we present a three-dimensional, hydrogel-based sensor the structure of which is fabricated in a single step using thermal nanoimprint lithography. The sensor is based on a waveguide with a grating readout section. A specific hydrogel formulation, based on a combination of PEGDMA (Poly(Ethylene Glycol DiMethAcrylate)), NIPAAm (N-IsoPropylAcrylAmide), and AA (Acrylic Acid), was developed. This stimulus-responsive hydrogel is sensitive to pH and to water. Moreover, the hydrogel has been modified to be suitable for fabrication by thermal nanoimprint lithography. Once stimulated, the hydrogel-based sensor changes its topography, which is characterised physically by AFM and SEM, and optically using a specific optical set-up.
| Item Type: | Articles |
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| Additional Information: | The authors acknowledge the financial support from: the EU project, NAPANIL project (No. FP7-CP-IP 214249), the MINECO project PHENTOM (No. FIS2015-70862). ICN2 acknowledges support from the Severo Ochoa Program (MINECO, Grant SEV-2013-0295) and funding from the CERCA Programme/Generalitat de Catalunya. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Gadegaard, Professor Nikolaj |
| Authors: | Francone, A., Kehoe, T., Obieta, I., Saez-Martinez, V., Bilbao, L., Khokhar, A., Gadegaard, N., Simao, C., Kehagias, N., and Sotomayor Torres, C. |
| College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Sensors |
| Publisher: | MDPI |
| ISSN: | 1424-8220 |
| ISSN (Online): | 1424-8220 |
| Published Online: | 26 September 2018 |
| Copyright Holders: | Copyright © 2018 The Authors |
| First Published: | First published in Sensors 18(10): 3240 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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