Walking pace is associated with lower risk of all-cause and cause-specific mortality

Celis-Morales, C. A. et al. (2019) Walking pace is associated with lower risk of all-cause and cause-specific mortality. Medicine and Science in Sports and Exercise, 51(3), pp. 472-480. (doi: 10.1249/MSS.0000000000001795) (PMID:30303933)

Abstract

Purpose: Walking pace is associated with all-cause and cardiovascular disease (CVD) mortality. Whether this association extends to other health outcomes and whether it is independent of total amount of time walked are currently unknown. Therefore, the aim of this study was to investigate whether usual walking pace is associated with a range of health outcomes. Methods: 318,185 UK Biobank participants (54% women) aged 40-69 years were included. Walking pace and total walking time were self-reported. The outcomes comprised: all-cause mortality as well as incidence and mortality from cardiovascular disease (CVD), respiratory disease and cancer. The associations were investigated using Cox proportional hazard models. Results: Over a mean of 5.0 years [ranging from 3.3 to 7.8], 5,890 participants died, 18,568 developed CVD, 5,430 respiratory disease and 19,234 cancer. In a fully adjusted model, compared to slow pace walkers, men and women, respectively, with a brisk pace having lower risk of mortality from all-causes (HR0.79 [95% CI: 0.69; 0.90] and 0.73 [95% CI: 0.62; 0.85]), CVD (HR 0.62 [0.50; 0.76] and 0.80 [0.73; 0.88]), respiratory disease (HR 0.58 [95% CI 0.43; 0.78] and 0.66 [0.57; 0.77]), COPD (HR 0.26 [95% 0.12; 0.56] and 0.28 [0.16; 0.49]). No associations were found for all-cause cancer, colorectal, breast cancer. However, brisk walking was associated with a higher risk of prostate cancer. Conclusions: Walking pace is associated with lower risk of a wide range of important health conditions, independently of overall time spent walking.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Gill, Professor Jason and Anderson, Dr Jana and Welsh, Professor Paul and Celis, Dr Carlos and Gray, Professor Stuart and Iliodromiti, Dr Stamatina and Pell, Professor Jill and Petermann-Rocha, Mrs Fanny and Sattar, Professor Naveed and Pellicori, Dr Pierpaolo and Lyall, Dr Donald
• Authors: Celis-Morales, C. A., Gray, S., Petermann, F., Iliodromiti, S., Welsh, P., Lyall, D. M., Anderson, J., Pellicori, P., Mackay, D. F., Pell, J. P., Sattar, N., and Gill, J. M.R.
• College/School: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health; College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health; College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Robertson Centre
• Journal Name: Medicine and Science in Sports and Exercise
• Publisher: American College of Sports Medicine
• ISSN: 0195-9131
• ISSN (Online): 1530-0315
• Published Online: 09 October 2018
• Copyright Holders: Copyright © 2018 American College of Sports Medicine
• First Published: First published in Medicine and Science in Sports and Exercise 51(3): 472-480
• Publisher Policy: Reproduced in accordance with the publisher copyright policy