Understanding influenza

Hutchinson, E. C. and Yamauchi, Y. (2018) Understanding influenza. In: Yamauchi, Y. (ed.) Influenza Virus. Series: Methods in molecular biology (1836). Humana Press: New York, NY, pp. 1-21. ISBN 9781493986774 (doi: 10.1007/978-1-4939-8678-1_1)

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Influenza, a serious illness of humans and domesticated animals, has been studied intensively for many years. It therefore provides an example of how much we can learn from detailed studies of an infectious disease and of how even the most intensive scientific research leaves further questions to answer. This introduction is written for researchers who have become interested in one of these unanswered questions, but who may not have previously worked on influenza. To investigate these questions, researchers must not only have a firm grasp of relevant methods and protocols; they must also be familiar with the basic details of our current understanding of influenza. This article therefore briefly covers the burden of disease that has driven influenza research, summarizes how our thinking about influenza has evolved over time, and sets out key features of influenza viruses by discussing how we classify them and what we understand of their replication. It does not aim to be comprehensive, as any researcher will read deeply into the specific areas that have grasped their interest. Instead, it aims to provide a general summary of how we came to think about influenza in the way we do now, in the hope that the reader’s own research will help us to understand it better.

Item Type:Book Sections
Additional Information:Online ISBN: 9781493986781.
Glasgow Author(s) Enlighten ID:Hutchinson, Dr Ed
Authors: Hutchinson, E. C., and Yamauchi, Y.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
Publisher:Humana Press
Published Online:28 August 2018
Copyright Holders:Copyright © 2018 Springer Science+Business Media B.V., part of Springer Nature
First Published:First published in Influenza Virus: 1-21
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
703851Functional investigations of the influenza virus proteomeEdward HutchinsonMedical Research Council (MRC)MR/N008618/1MVLS III - CENTRE FOR VIRUS RESEARCH