Ng'habi, K., Viana, M. , Matthiopoulos, J. , Lyimo, I., Killeen, G. and Ferguson, H. M. (2018) Mesocosm experiments reveal the impact of mosquito control measures on malaria vector life history and population dynamics. Scientific Reports, 8, 13949. (doi: 10.1038/s41598-018-31805-8) (PMID:30224714) (PMCID:PMC6141522)
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Abstract
The impact of control measures on mosquito vector fitness and demography is usually estimated from bioassays or indirect variables in the field. Whilst indicative, neither approach is sufficient to quantify the potentially complex response of mosquito populations to combined interventions. Here, large replicated mesocosms were used to measure the population-level response of the malaria vector Anopheles arabiensis to long-lasting insecticidal nets (LLINs) when used in isolation, or combined with insecticidal eave louvers (EL), or treatment of cattle with the endectocide Ivermectin (IM). State-space models (SSM) were fit to these experimental data, revealing that LLIN introduction reduced adult mosquito survival by 91% but allowed population persistence. ELs provided no additional benefit, but IM reduced mosquito fecundity by 59% and nearly eliminated all populations when combined with LLINs. This highlights the value of IM for integrated vector control, and mesocosm population experiments combined with SSM for identifying optimal combinations for vector population elimination.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Ferguson, Professor Heather and Matthiopoulos, Professor Jason and Viana, Dr Mafalda |
| Authors: | Ng'habi, K., Viana, M., Matthiopoulos, J., Lyimo, I., Killeen, G., and Ferguson, H. M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
| Journal Name: | Scientific Reports |
| Publisher: | Nature Research |
| ISSN: | 2045-2322 |
| ISSN (Online): | 2045-2322 |
| Copyright Holders: | Copyright © 2018 The Authors |
| First Published: | First published in Scientific Reports 8:13949 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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