The neurobiology of acute pain

Bell, A. (2018) The neurobiology of acute pain. Veterinary Journal, 237, pp. 55-62. (doi: 10.1016/j.tvjl.2018.05.004) (PMID:30089546)

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The mechanisms by which noxious stimuli produce the sensation of pain in animals are complex. Noxious stimuli are transduced at the periphery and transmitted to the CNS, where this information is subject to considerable modulation. Finally, the information is projected to the brain where it is perceived as pain. Additionally, plasticity can develop in the pain pathway and hyperalgesia and allodynia may develop through sensitisation both peripherally and centrally. A large number of different ion channels, receptors, and cell types are involved in pain perception, and it is hoped that through a better understanding of these, new and refined treatments for pain will result.

Item Type:Articles
Keywords:Analgesia, neurobiology, nociception, pain, spinal cord.
Glasgow Author(s) Enlighten ID:Bell, Mr Andrew
Authors: Bell, A.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Veterinary Journal
ISSN (Online):1532-2971
Published Online:20 May 2018
Copyright Holders:Copyright © 2018 Crown Copyright
First Published:First published in Veterinary Journal 237: 55-62
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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