Harper, M. M., Connolly, M. L., Goldie, L., Irvine, E. J., Shaw, J. E., Jayawarna, V., Richardson, S. M., Dalby, M. J. , Lightbody, D. and Ulijn, R. V. (2018) Biogelx: cell culture on self-assembling peptide gels. In: Nilsson, B. L. and Doran, T. M. (eds.) Peptide Self-Assembly: Methods and Protocols. Series: Methods in molecular biology (1777). Humana Press: New York, NY, pp. 283-303. ISBN 9781493978090 (doi: 10.1007/978-1-4939-7811-3_18)
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Abstract
Aromatic peptide amphiphiles can form self-supporting nanostructured hydrogels with tunable mechanical properties and chemical compositions. These hydrogels are increasingly applied in two-dimensional (2D) and three-dimensional (3D) cell culture, where there is a rapidly growing need to store, grow, proliferate, and manipulate naturally derived cells within a hydrated, 3D matrix. Biogelx Limited is a biomaterials company, created to commercialize these bio-inspired hydrogels to cell biologists for a range of cell culture applications. This chapter describes methods of various characterization and cell culture techniques specifically optimized for compatibility with Biogelx products.
| Item Type: | Book Sections |
|---|---|
| Keywords: | Biomaterials, cell culture, hydrogels, self-assembly. |
| Status: | Published |
| Glasgow Author(s) Enlighten ID: | Jayawarna, Dr Vineetha and Dalby, Professor Matthew |
| Authors: | Harper, M. M., Connolly, M. L., Goldie, L., Irvine, E. J., Shaw, J. E., Jayawarna, V., Richardson, S. M., Dalby, M. J., Lightbody, D., and Ulijn, R. V. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Molecular Biosciences College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Publisher: | Humana Press |
| ISBN: | 9781493978090 |
| Published Online: | 10 May 2018 |
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