DNA sequence of surface antigen gene gp195 of two Chinese isolates of Plasmodium falciparum from Hainan

Guan, W.B., Walliker, D., Ranford-Cartwright, L. , Zhang, L.Q. and Qu, D. (1992) DNA sequence of surface antigen gene gp195 of two Chinese isolates of Plasmodium falciparum from Hainan. Chinese Journal of Parasitology and Parasitic Diseases, 10(2), pp. 90-94. (PMID:1394915)

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Abstract

Amplification of DNA sequence of surface antigen gene, block II of gp195 from 2 Chinese isolates of Plasmodium falciparum FCC 7801/HN B3 and FCC M21/HN from Hainan, China, was established by using the polymerase chain reaction. A comparison of the 154 peptide sequences of the 2 Chinese isolates showed that they were identical, but there was a difference of 10 peptides among the established 154 peptides between the two Chinese isolates and MAD 20 (a Papua New Guinea isolate). The need to determine the fragments having protective effect against malarial infection, and to study the genetic basis of the antigen polymorphism of Chinese strains of Plasmodium falciparum is evident.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ranford-Cartwright, Dr Lisa
Authors: Guan, W.B., Walliker, D., Ranford-Cartwright, L., Zhang, L.Q., and Qu, D.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Chinese Journal of Parasitology and Parasitic Diseases
Publisher:Chinese Academy of Preventive Medicine, Institute of Parasitic Diseases
ISSN:1000-7423

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