Aboumarzouk, O. M. et al. (2018) What Is the role of α-blockers for medical expulsive therapy? Results from a meta-analysis of 60 randomized trials and over 9500 patients. Urology, 119, pp. 5-16. (doi: 10.1016/j.urology.2018.03.028) (PMID:29626570)
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Abstract
Use of α-blockers for medical expulsive therapy (MET) has been the subject of huge debate in Urology. Moreover, there have been a number of randomised controlled trials (RCTs) with differing results. We conducted a systematic review and meta-analysis of RCTs investigating the efficacy α-blockers for MET. This review confirms there is a role for α-blockers in medical expulsive therapy for ureteric stones specifically in stones >5mm and distal ureteric stones, which is associated with improved stone expulsion. However, there is a slight increase in risk of non-significant side effects. [Abstract copyright: Copyright © 2018. Published by Elsevier Inc.]
| Item Type: | Articles |
|---|---|
| Keywords: | MET, Ureteric stones, medical expulsive therapy, urinary stones, α-blockers |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Aboumarzouk, Mr Omar |
| Authors: | Aboumarzouk, O. M., Jones, P., Amer, T., Kotsiris, D., Emiliani, E., Somani, B., Kallidonis, P., Tailly, T., Atis, G., Greco, F., Hruby, S., Alvarez, M., Al-Rumaihi, K., Shamsuddin, A., Al-Ansari, A., and Shokeir, A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
| Journal Name: | Urology |
| Publisher: | Elsevier |
| ISSN: | 0090-4295 |
| ISSN (Online): | 1527-9995 |
| Published Online: | 04 April 2018 |
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