Novel parvoviruses from wild and domestic animals in Brazil provide new insights into parvovirus distribution and diversity

de Souza, W. M. et al. (2018) Novel parvoviruses from wild and domestic animals in Brazil provide new insights into parvovirus distribution and diversity. Viruses, 10(4), 143. (doi: 10.3390/v10040143) (PMID:29565808) (PMCID:PMC5923437)

Abstract

Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified. In this study, we used high-throughput sequencing (HTS) to investigate the diversity of parvoviruses infecting wild and domestic animals in Brazil. We identified 21 parvovirus sequences (including twelve nearly complete genomes and nine partial genomes) in samples derived from rodents, bats, opossums, birds and cattle in Pernambuco, São Paulo, Paraná and Rio Grande do Sul states. These sequences were investigated using phylogenetic and distance-based approaches and were thereby classified into eight parvovirus species (six of which have not been described previously), representing six distinct genera in the subfamily Parvovirinae. Our findings extend the known biogeographic range of previously characterized parvovirus species and the known host range of three parvovirus genera (Dependovirus, Aveparvovirus and Tetraparvovirus). Moreover, our investigation provides a window into the ecological dynamics of parvovirus infections in vertebrates, revealing that many parvovirus genera contain well-defined sub-lineages that circulate widely throughout the world within particular taxonomic groups of hosts.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Olszanski Acrani, Mr Gustavo and Gifford, Dr Robert and Dennis, Tristan and Modha, Ms Sejal
• Authors: de Souza, W. M., Dennis, T., Fumagalli, M. J., de Araujo, J., Sabino-Santos Jr., G., Gonçalves Motta Maia, F., Olszanski Acrani, G., de Oliveira Torres Carrasco, A., Romeiro, M. F., Modha, S., Vieira, L. C., Ometto, T., Queiroz, L. H., Durigon, E. L., Nunes, M. R. T., Figueiredo, L. T. M., and Gifford, R. J.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity; College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
• Journal Name: Viruses
• Publisher: MDPI
• ISSN: 1999-4915
• ISSN (Online): 1999-4915
• Copyright Holders: Copyright © 2018 The Authors
• First Published: First published in Viruses 10(4):143
• Publisher Policy: Reproduced under a Creative Commons License