Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross-sectional study of 500000 UK Biobank participants

Ferguson, L.D. , Ntuk, U.E., Celis-Morales, C. , Mackay, D.F. , Pell, J.P. , Gill, J.M.R. and Sattar, N. (2018) Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross-sectional study of 500000 UK Biobank participants. Diabetic Medicine, 35(2), pp. 270-276. (doi: 10.1111/dme.13551) (PMID:29171078)

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Abstract

Aims: Studies show that white men have a higher prevalence of Type 2 diabetes mellitus than women at a given age and BMI, but equivalent standardized data for other ethnic groups in the UK are sparse. Methods: This cross-sectional study analysed UK Biobank data from 489 079 participants to compare the prevalence of diabetes mellitus across four major ethnic groups including: 471 700 (96.4%) white, 7871 (1.6%) South Asian, 7974 (1.6%) black and 1534 (0.3%) Chinese participants, before and after standardizing for age, socio-economic status (SES), BMI and lifestyle factors including physical activity, TV viewing, fruit and vegetable intake, processed meat, red meat, oily fish, alcohol intake and smoking. A subgroup analysis of South Asians was also undertaken. Results: Crude diabetes prevalence was higher in men across all four ethnicities. After standardizing for age, SES, BMI and lifestyle factors, a significant sex difference in diabetes prevalence persisted in white (men 6.0% vs. women 3.6%), South Asian (21.0% vs. 13.8%) and black individuals (13.3% vs. 9.7%) (P < 0.0001); there was a non-significant difference between Chinese men and women (7.1% vs. 5.5%) (P = 0.211). Sex differences persisted across South Asian subgroups. Conclusions: Men across a range of major ethnic groups including white, South Asian and black, have a higher prevalence of diabetes compared with women of similar age, BMI, SES and lifestyle in the UK.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gill, Professor Jason and Mackay, Professor Daniel and Ntuk, Uduakobong Efanga and Ferguson, Dr Lyn and Celis, Dr Carlos and Pell, Professor Jill and Sattar, Professor Naveed
Authors: Ferguson, L.D., Ntuk, U.E., Celis-Morales, C., Mackay, D.F., Pell, J.P., Gill, J.M.R., and Sattar, N.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health
Journal Name:Diabetic Medicine
Publisher:Wiley
ISSN:0742-3071
ISSN (Online):1464-5491
Published Online:24 November 2017
Copyright Holders:Copyright © 2017 Diabetes UK
First Published:First published in Diabetic Medicine 35(2): 270-276
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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