Carles, G. , Muyo, G., van Hemert, J. and Harvey, A. R. (2017) Combined high contrast and wide field-of-view in the Scanning Laser Ophthalmoscope through dual detection of light paths. Journal of Biomedical Optics, 22(1), 116002. (doi: 10.1117/1.JBO.22.11.116002)
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Abstract
We demonstrate a multimode detection system in a scanning laser ophthalmoscope (SLO) that enables simultaneous operation in confocal, indirect, and direct modes to permit an agile trade between image contrast and optical sensitivity across the retinal field of view to optimize the overall imaging performance, enabling increased contrast in very wide-field operation. We demonstrate the method on a wide-field SLO employing a hybrid pinhole at its image plane, to yield a twofold increase in vasculature contrast in the central retina compared to its conventional direct mode while retaining high-quality imaging across a wide field of the retina, of up to 200 deg and 20 μm on-axis resolution.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Carles Santacana, Dr Guillem and Harvey, Professor Andy |
| Authors: | Carles, G., Muyo, G., van Hemert, J., and Harvey, A. R. |
| College/School: | College of Science and Engineering > School of Physics and Astronomy |
| Journal Name: | Journal of Biomedical Optics |
| Publisher: | Society of Photo-optical Instrumentation Engineers |
| ISSN: | 1083-3668 |
| ISSN (Online): | 1560-2281 |
| Published Online: | 02 November 2017 |
| Copyright Holders: | Copyright © 2017 The Authors |
| First Published: | First published in Journal of Biomedical Optics 22(1): 116002 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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